Effects of TPPS2a-Photosensitization Lysosomal Membranes
نویسندگان
چکیده
منابع مشابه
Permeability properties of lysosomal membranes.
Lysosomes are involved in the cellular degradation of material either initially present in the cell or brought into the cell by phagocytosis or endocytosis. This degradative process, which occurs in an acidic environment, produces metabolites such as peptides and amino acids~ nucleos ides , and sugars which may subsequently accumulate within the lysosome. It is therefore important for osmotic r...
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Membranes were prepared from lysosomes purified 80-fold by centrifugation in a discontinuous metrizamide gradient. When salt-washed membranes were combined with rabbit muscle actin, an increase in viscosity could be measured using a falling ball viscometer. The lysosomal membrane-actin interaction was actin- and membrane-concentration dependent and appeared to be optimal under presumed physiolo...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2018
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2017.11.1511